发明名称 4-FLUOROBENZOIC DERIVATIVES,PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The invention relates to the compounds of general formula I: <IMAGE> (I) in which: m represents an integer from 2 to 4, n and p, which may be identical or different, each represent an integer from 1 to 3, q represents 0 or 1, and R represents: either a group of formula (A): <IMAGE> (A) or a radical of formula (B): <IMAGE> (B) or a 2,4-dioxo-1,2,3,4-tetrahydroquinazolinyl radical, on condition, however, that, in this case, n and p do not simultaneously represent the number 2, or a benzhydryloxy group, or a 1-oxophthalazinyl radical, or a 5-oxothiazolo[3,2-A]pyrimidinyl radical, or a group of formula C: <IMAGE> (C) their possible stereoisomers and their addition salts with a pharmaceutically acceptable inorganic or organic acid. The compounds of formula I are medicinal products with useful 5-HT2- and alpha 1-antagonistic activities.
申请公布号 ZA9002142(B) 申请公布日期 1990.12.28
申请号 ZA19900002142 申请日期 1990.03.20
申请人 ADIR ET COMPAGNIE 发明人 GILBERT LAVIELLE;FRANCIS COLPAERT;MICHEL LAUBIE
分类号 A61K31/335;A61K31/4427;A61K31/443;A61K31/445;A61K31/451;A61K31/495;A61K31/505;A61P25/00;A61P25/02;A61P43/00;C07D207/08;C07D211/32;C07D401/06;C07D401/12;C07D401/14;C07D403/06;C07D403/12;C07D403/14;C07D405/06;C07D405/12;C07D487/04;C07D513/04 主分类号 A61K31/335
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