发明名称 ANTIFUNGAL 4-(4-(4-(4-((2-(2,4-DIFLUOROPHENYL)-2-(IH- AZOLYLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)- 1-PIPERAZINYL)PHENYL)TRIAZOLONES AND IMIDAZOLONES
摘要 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4 -yl]methoxy]pheny l ]-1-piperazinyl]phenyl]triazolones and imidazolones of formula <CHEM> wherein Q is CH or N; Y is a radical of formula <CHEM> R<1> is C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl; and R<2> is C1-6alkyl, C5-7cycloalkyl or mono-, di-, tri-, tetra- or pentahaloC1-4alkyl, the acid addition salts and stereoisomeric forms thereof; said compounds having antifungal properties. Pharmaceutical compositions containing such compounds as an active ingredient; methods of preparing said compounds and pharmaceutical compositions.
申请公布号 AU5689490(A) 申请公布日期 1990.12.13
申请号 AU19900056894 申请日期 1990.06.07
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 HANS HEERES;LEO JACOBUS JOZEF BACKX
分类号 C07D405/14;A61K31/00;A61K31/41;A61K31/415;A61K31/4166;A61K31/4245;A61K31/495;A61K31/496;A61P31/00;A61P31/04;A61P31/10;C07D521/00 主分类号 C07D405/14
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