| 发明名称 |
DOMINANT NEGATIVE MEMBERS OF THE STEROID/THYROID SUPERFAMILY OF RECEPTORS |
| 摘要 |
2057049 9014356 PCTABS00002 Disclosed are novel trans-repressing analog receptors wherein the ligand-binding domain(s) are modified versus wild type receptor, such novel receptors having repressed trans-activation transcription activation properties. Also disclosed are recombinant methods and means for preparing such receptors and assays using such receptors.
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| 申请公布号 |
CA2057049(A1) |
申请公布日期 |
1990.11.27 |
| 申请号 |
CA19902057049 |
申请日期 |
1990.05.25 |
| 申请人 |
SALK INSTITUTE FOR BIOLOGICAL STUDIES (THE) |
发明人 |
EVANS, RONALD M.;HOLLENBERG, STANELY M.;ORO, ANTHONY E.;DAMM, KLAUS;HEYMAN, RICHARD A. |
| 分类号 |
A01K67/027;A61K38/00;A61P5/00;C07K14/705;C07K14/72;C12N5/10;C12N15/09;C12P21/02;C12R1/91;(IPC1-7):C12N15/62;C07K19/00;G01N33/68 |
主分类号 |
A01K67/027 |
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