发明名称 |
Method to enhance NMR imaging using chelated paramagnetic ions |
摘要 |
Agents useful for influencing the relaxation times in NMR diagnostics, contain at least one paramagnetic, physiologically compatible complex salt comprising a chelate from an open-chain or cyclic complex-forming compound containing organic nitrogen, phosphorus, oxygen and/or sulfur, and a complexed ion of the lanthanide elements of atomic number 57-70 or of the transition metals of atomic numbers 21-29, 42 and 44, and, optionally, an inorganic or organic base or acid.
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申请公布号 |
US4963344(A) |
申请公布日期 |
1990.10.16 |
申请号 |
US19890370139 |
申请日期 |
1989.06.23 |
申请人 |
SCHERING AG |
发明人 |
GRIES, HEINZ;ROSENBERG, DOUWE;WEINMANN, HANNS-JOACHIM;SPECK, ULRICH;MUTZEL, WOLFGANG;HAYDEN, GEORG-ALEXANDER;PFEIFFER, HEINRICH |
分类号 |
A61K49/04;A61K49/06;A61K49/10;A61K49/18;C07C323/25;C07D257/02;C07F9/38;G01R33/28 |
主分类号 |
A61K49/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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