| 摘要 |
<p>The present invention relates to new 1,3-dioxolan-4-yl derivatives of 2-picolylamine having the formula (I): <CHEM> wherein: R1 represents an alkyl or phenylalkyl radical; R2 represents hydrogen, C1-C4-acyl or C1-C4-alkoxycarbonyl; R3 is either an electron pair, in which case t means nothing and q is zero, or R3 is hydrogen or C1-C4-alkyl, in which case t is (+) and q=1; X is a single bond, an oxygen atom or a carbamoyloxy group; A<-> is a pharmaceutically acceptable anion. These compounds are PAF antagonists and, consequently, useful in the treatment of the diseases in which this substance is involved.</p> |
