| 摘要 |
<p>NEW MATERIAL:Compounds expressed by formula I [X<1> and Y<1> are H or both together form single bond; X<2> and Y<2> are H or both together form single bond; Y<3> is H or OH; R<1> and R<2> are H, (substituted) lower alkyl, (substituted) aryl, (substituted) 4-piperidyl, pyridyl, isoquinolyl, etc., or together with N to which both are linked, form 5- or 6-membered heterocyclic ring, etc.; R<4> is lower alkyl; R<5> is H or CH3; l and n are 0-2; m is 0 or 1]. EXAMPLE:Ethyl 2-[2-(1H-imidazol-1-yl)-1-hydroxyethyl]-2,6,10-trimethylundecanoate expressed by formula IV. USE:A medicine which is an active ingredient of ameliorants for cerebral function, having high safety and used as a drug for treating cerebral ischemia, cerebral hypoxemia, etc., in an acute or chronic period. PREPARATION:For example, an epoxy compound expressed by formula II is reacted with a nitrogen-containing compound expressed by formula III while being heated to afford the compounds expressed by formula I (Y<3> is OH).</p> |
