Novel 1,7-fused 1H-indole-N-(5-phenyl-1,4-benzodiazepin-3-yl)-2-carboxamides

摘要

Compounds of the general formula I <IMAGE> are described in which R<1> is hydrogen, lower alkyl or cycloalkylalkyl having 4-7 carbon atoms, R<2> is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl and R<3> is hydrogen, halogen, lower alkyl or lower alkoxy or R<2> and R<3> together are alkylenedioxy, R<4> is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl, R<5> is hydrogen, halogen, lower alkyl or lower alkoxy, R<6> is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl, R<7> is hydrogen, lower alkyl or halogen and Z is an alkylene chain having 2-4 carbon atoms, which can optionally be mono- or disubstituted by lower alkyl or to which a 5-6-membered carbocyclic ring can optionally be fused, or is an -X-CH2-CH2- chain. The compounds have pharmacologically useful properties.