发明名称 |
Purified C5a receptor from human polymorphonuclear leukocytes. |
摘要 |
<p>A method is disclosed for isolating and purifying C5a receptor from human polymorphonuclear leukocytes. C5a is a complement-derived protein which is important as a mediator of inflammatory responses. C5a receptor may be used to screen create and quantify C5a antagonists useful as anti-inflammatory agents and immunoregulants and to generate monoclonal and polyclonal anti-C5a receptor antibodies useful as anti-inflammatory agents and immunoregulants.</p> |
申请公布号 |
EP0377489(A2) |
申请公布日期 |
1990.07.11 |
申请号 |
EP19900300012 |
申请日期 |
1990.01.02 |
申请人 |
MERCK & CO. INC. |
发明人 |
ROLLINS, THOMAS E.;SPRINGER, MARTIN S. |
分类号 |
C12P21/08;A61K38/00;A61P37/00;C07K1/22;C07K14/435;C07K14/705 |
主分类号 |
C12P21/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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