Carbamoyl-2-pyrrolidinone compounds.

摘要

(a) nootropic agents containing 1-carbamoyl-2-pyrrolidinones of formula (I) as active component: where R1 is H, OH or lower alkyl (opt. substd. by hydroxy); R2 is phenyl, tetrahydronaphthyl, pyridyl or thiazolyl opt. substd. by lower alkoxy, lower alkylamino, halogen or halomethyl). (b) Compounds (I) are new, where R2 is phenyl, tetrahydronaphthyl, pyridyl or thiazolyl opt. substd. by methoxy or lower alkylamino; and R1 is as defined above; with the proviso that when R1 is H or unsubstd. lower alkyl, then R2 is not unsubstd. phenyl. New compounds (I) where R1 is H, OH, methyl or hydroxymethyl (pref. H or OH); R2 is phenyl, tetrahydronaphthyl, pyridyl or thiazolyl opt. substd. by 1 to 3 methoxy groups or dimethylamino (pref. phenyl or tetrahydronaphthyl opt. substd. by methoxy).