发明名称 |
Antiemesis ergoline derivatives. |
摘要 |
<p>Compounds of the formula I <CHEM> wherein n is 1 or 2, R1 represents a hydrogen atom or a C1-C4 alkyl group, R2 represents a hydrogen atom and R3 represents a hydrogen atom or a hydroxy group or R2 and R3 together represent a chemical bond, R4 represents a hydrogen atom, or a phenyl or C1-C4 alkyl group, R5 represents a C1-C4 alkyl group or an allyl group and R6 represents a hydrogen or halogen atom, and the pharmaceutically acceptable salt thereof, are useful for the manufacture of a pharmaceutical composition useful in the treatment of emesis.</p> |
申请公布号 |
EP0371246(A1) |
申请公布日期 |
1990.06.06 |
申请号 |
EP19890119544 |
申请日期 |
1989.10.20 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
ROSSI, ALESSANDRO;BUONAMICI, METILDE;PEGRASSI, LORENZO;BRAMBILLA, ENZO |
分类号 |
C07D457/02;A61K31/48;A61K31/495;A61P1/08 |
主分类号 |
C07D457/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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