PROCESS FOR PRODUCING ALPHA-APM

摘要

Dissolve alpha-L-aspartyl-L-phenylalain 35.8g (contg. 22 wt.% of beta-L-aspartyl-L-phenylalanin) in soln. of conc. H2SO4 30g, water 97.8g and MeOH 9.6g; react with MgCl2 for 4 day at 30-35 deg. C; cool to 20 deg. C and filter; and wash with cold water to give alpha-APM hydrochloride (as alpha-APM 23.4g). The alpha-APM is useful as a sweetener.