| 摘要 |
NEW MATERIAL:The compound of formula I (X is daunosamine-rhodenose, etc., when R<1> and R<2> are OH, R<3> is ethyl and R<4> is methoxycarbonyl or R<1> and R<2> are OH, R<3> is 1-hydroxyethyl and R<4> is H or R<1> is methoxy, R<2> is OH, R<3> is ethyl and R<4> is methoxycarbonyl; X is rhodosamine-rhodenose, etc., when R<1>, R<2> and R<4> are OH R<3> is ethyl; X is rhodosamine-deoxyfucose when R<1> and R<4> are OH, R<2> is H and R<3> is ethyl) and its salt. EXAMPLE:The compound of formula II. USE:An antitumor agent. PREPARATION:The objective compound can be produced e.g., by the microbiological treatment of an anthracycline D788-6 substance of formula III (R<1> and R<2> are OH; R<3> is ethyl; R<4> is methoxycarbonyl; X' is daunosamine) with Streptomyces galilaeus MA144-M1, KE303 strain (FERM P-4808). |
