发明名称 Influenza vaccine and novel adjuvants.
摘要 An influenza immunizing dosage form comprising a liposome and an antigen of Influenza, particularly the hemagglutinin or bromelain fragment, wherein said liposome and antigen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt form of an organic acid derivative of a sterol and an antigen wherein said organic acid derivative of a sterol and antigen are present in an immunization dose, and method of use. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristolyphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an antigen wherein said DMPC/cholesterol and antigen are present in an immunization dose, and method of use.
申请公布号 EP0356339(A1) 申请公布日期 1990.02.28
申请号 EP19890402343 申请日期 1989.08.25
申请人 THE LIPOSOME COMPANY, INC. 发明人 POPESCU, MIRCEA C.;RECINE, MARIE S.;ALVING, CARL L.;ESTIS, LEONARD F.;KEYES, LYNN D.;JANOFF, ANDREW S.
分类号 A61K38/00;A61K9/00;A61K9/127;A61K38/36;A61K39/00;A61K39/12;A61K39/145;B01J13/02 主分类号 A61K38/00
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