发明名称 |
Influenza vaccine and novel adjuvants. |
摘要 |
An influenza immunizing dosage form comprising a liposome and an antigen of Influenza, particularly the hemagglutinin or bromelain fragment, wherein said liposome and antigen are present in an immunization dose. Additionally, a dosage form, including such form particularly adapted to producing an immune response, comprising a salt form of an organic acid derivative of a sterol and an antigen wherein said organic acid derivative of a sterol and antigen are present in an immunization dose, and method of use. Further, a dosage form, including such form particularly adapted to producing an immune response, comprising dimyristolyphosphatidylcholine (DMPC)/cholesterol liposomes, optionally in an aluminum hydroxide gel, and an antigen wherein said DMPC/cholesterol and antigen are present in an immunization dose, and method of use. |
申请公布号 |
EP0356339(A1) |
申请公布日期 |
1990.02.28 |
申请号 |
EP19890402343 |
申请日期 |
1989.08.25 |
申请人 |
THE LIPOSOME COMPANY, INC. |
发明人 |
POPESCU, MIRCEA C.;RECINE, MARIE S.;ALVING, CARL L.;ESTIS, LEONARD F.;KEYES, LYNN D.;JANOFF, ANDREW S. |
分类号 |
A61K38/00;A61K9/00;A61K9/127;A61K38/36;A61K39/00;A61K39/12;A61K39/145;B01J13/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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