| 发明名称 |
Process and composition for the purification of amphotericin B |
| 摘要 |
A unique four-solvent system comprising methanol, dimethylformamide, methylene chloride and water is employed to provide an improved process for the purification and crystallization of amphotericin B.
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| 申请公布号 |
US4902789(A) |
申请公布日期 |
1990.02.20 |
| 申请号 |
US19870113790 |
申请日期 |
1987.10.27 |
| 申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
MICHEL, GERD W.;BRYAN, WILBUR L.;BRYAN, ELIZABETH |
| 分类号 |
A61K31/70;A61K31/7042;A61K31/7048;C07H1/06;C07H17/08 |
主分类号 |
A61K31/70 |
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