| 摘要 |
NEW MATERIAL:The compound of formula I [R<1> and R<2> are H, lower alkyl, lower alkoxy, halogenated lower alkyl, halogen, etc.; R<3> and R<4> are H or lower alkyl; m is 2-10; Z is -OR<5> (R<5> is H, lower alkyl, aryl, etc.) or -O-(CH2)n-O-R<6> (n is 1-3; R<6> is H, lower alkyl, aryl, etc.); X<-> is anion]. EXAMPLE:3-(3-Methoxy)propoxy-4-methyl-5H-pyrido[1',2':4,5][1,2,4]-thia diazino[2,3- a]benzimidazol-13-ium tetrafluoroborate. USE:An antiulcer agent having excellent action to suppress the secretion of gastric acid. PREPARATION:A pyridine derivative of formula III is subjected to thermal reaction in the presence of an acid. |
