摘要 |
Compounds having detergent properties are disclosed. When a modifying reagent is brought into contact with these compounds, the detergent properties are decreased. These compounds are useful, for example, as solubilizing agents for microbial antigens and/or antibodies and for reversibly wetting hydrophobic surfaces. Accordingly, methods are disclosed for increasing the hydrophilic properties of a material, such as a microbial antigen and/or antibody, the methods generally comprising the steps of contacting the material with the compound having detergent properties and a modifiable group, and modifying the compound with a modifying reagent. Kits are also disclosed for use in accordance with this methodology. |
申请人 |
SYNTEX (U.S.A.) INC., PALO ALTO, CALIF., US |
发明人 |
SWITCHENKO, ARTHUR C.;KURN, NURITH, PALO ALTO, CALIF., US;ULLMAN, EDWIN F., ATHERTON, CALIF., US;PIRIO, MARCEL;BERGER JUN., DONALD E., SAN JOSE, CALIF., US;NEUKOM, CHRISTIAN, MOUNTAIN VIEW, CALIF., US |