发明名称 Antipsychotic 3-piperazinyl-benzazole derivatives.
摘要 Novel 3-piperazinyl-1,2-benzazoles of formula <CHEM> wherein Q is a radical of formula <CHEM> R is hydrogen or C1-6alkyl; R<1> and R<2> are hydrogen, halo, hydroxy, C1-6alkyloxy or C1-6alkyl; X is O, S or NR<3>; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, which compounds are antipsychotic agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
申请公布号 EP0353821(A2) 申请公布日期 1990.02.07
申请号 EP19890201981 申请日期 1989.07.28
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 KENNIS, LUDO EDMOND JOSEPHINE;VANDENBERK, JAN;MERTENS, JOSEPHUS CAROLUS
分类号 C07D417/04;A61K31/496;A61K31/505;A61K31/517;A61K31/54;A61P25/00;A61P25/02;A61P43/00;C07D231/56;C07D261/20;C07D275/04;C07D403/12;C07D413/12;C07D417/12;C07D471/04;C07D498/04;C07D513/04 主分类号 C07D417/04
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