摘要 |
<p>The present invention relates to novel imidazo[2,1-b]benzothiazole compounds represented by formula (I) and pharmacological acceptable salts thereof: <CHEM> wherein R1 represents a hydrogen atom or a lower alkyl group having 1 to 4 carbon atoms; R2 represents a <CHEM> group (wherein X and Y, which may be the same or different, each represents a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted phenyl group), a -CH2-O-Z group (wherein Z represents a lower alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted benzyl group) or a -CH2-O-CO-W group (wherein W represents an alkyl group having 1 to 8 carbon atoms, an alkylamino group having 1 to 8 carbon atoms, a substituted or unsubstituted phenyl group or a thienyl group); and R3, R4 and R5, which may be the same or different, each represents a hydrogen atom, a halogen atom or a lower alkoxy group having 1 to 4 carbon atoms and antiulcer compositions comprising as the effective ingredient the compounds.</p> |