发明名称 |
NUEVOS DERIVADOS DE 6- O 7-METILENOANDROSTA-1,4-DIENO3,17-DIONA Y PROCEDIMIENTO PARA SU PREPARACION. |
摘要 |
The invention relates to new 6- or 7-methylenandrosta-1,4-diene-3,17-diones of the following formula <CHEM> wherein R is hydrogen or fluorine; R1 is hydrogen or C1-C6 alkyl; R2 is hydrogen or halogen; one of R3 and R4 is =CH2 and the other is hydrogen or C1-C4 alkyl, and when R3 is =CH2, at least one of R and R4 is other than hydrogen; and the symbol @ @@ represents a double bond and the symbol @@@ represents a single bond when R3 is =CH2 or the symbol @@@ represents a single bond and the symbol @@@ represents a double bond when R4 is =CH2, which are useful in therapy, in particular as anti-cancer agents. |
申请公布号 |
ES2010513(B3) |
申请公布日期 |
1989.11.16 |
申请号 |
ES19870306125T |
申请日期 |
1987.07.10 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
DI SALLE, ENRICO;BARBUGIAN, NATALE;LOMBARDI, PAOLO;BUZZETTI, FRANCO |
分类号 |
A61K31/565;A61P35/00;C07J1/00;C07J21/00;C07J71/00 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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