| 发明名称 |
PROCESS FOR THE MANUFACTURE OF SPIRO-LINKED PYRROLIDINE-2,5 DIONES |
| 摘要 |
<p>Novel processes are disclosed for the manufacture of spiro-linked pyrrolidine-2,5-diones of the formula; which have potent inhibitory effects on aldose reductase and are useful for the reduction and prevention of chronic diabetic complications. These processes are useful as improved and convenient methods for large scale manufacture.</p> |
| 申请公布号 |
CA1261326(A) |
申请公布日期 |
1989.09.26 |
| 申请号 |
CA19870541568 |
申请日期 |
1987.07.08 |
| 申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
MASUZAWA, KUNIYOSHI;OKAMURA, KYUYA;FUJIMORI, SHIZUYOSHI;KINOSHITA, SUSUMU;MATSUKUBO, HIROSHI |
| 分类号 |
C07B61/00;C07D471/20;C07D498/20;C07D513/20;(IPC1-7):C07D471/20 |
主分类号 |
C07B61/00 |
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