| 摘要 |
Compounds of formula
<CHEM>
and their pharmaceutically acceptable salts are disclosed. R1is O or S; R2 is bromine or NHR where R is hydrogen or COR5 where R5 is alkyl of 1-4 carbon atoms, aryl or arylalkyl; and X and Y are each independently halogen, alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, trifluoromethyl, hydroxy, CN, SOnR3, COOR3, NR3R4, in which R3 and R4 are each independently hydrogen or alkyl of 1-4 carbon atoms and n is 0, 1, 2 or 3, and Y is further chosen from hydrogen. Also disclosed are a process for producing the compounds and pharmaceutical compounds comprising the compounds. The compounds are useful for treating autoimmune diseases. |
