| 摘要 |
PURPOSE:To obtain the title polylysine in high efficiency without the need for separation of bacteria from the fermented solution or heating and pressure reduction in the concentration, by treating an epsilon-polylysine-contg. solution with two kinds of ultrafiltration membranes differing in fractionation molecular weight from each other. CONSTITUTION:Firstly, a fermented culture solution produced by making a culture of microorganisms capable of producing epsilon-polylysine, or a culture solution produced by separating the bacteria from said culture solution is treated with a ultrafiltration membrane with a Fractionation molecular weight of >=3,000 [e.g., Filtron 3K (produced by Fuji Filter Ind. Ltd.)]. Thence, the resultant epsilon-polylysine-contg. solution as the filtrate is further treated with a second ultrafiltration membrane with a fractionation molecular weight of <=1,000 (e.g., Filtron 1K) to collect the monfilterable fraction. |
