| 摘要 |
PURPOSE: To increase a continuous layer of living epithelial cells over an artificial artery by specifying minute openings and the thickness of the part between them on the surface where cells are transposed and proliferate. CONSTITUTION: The maximum diameter of a minute opening on the surface where cells proliferate should be 0.1-3μm, and a part between openings on the surface should be 3μm thick at most. The blood vessel wall can be the polar or nonpolar mixture of styrene-butadiene-styrene block copolymer and, for example, polyurethane(PUR) or PUR-polysiloxane copolymer. The required minute opening forms a cross-reticular layer on the coarse surface where the opening exists. In the opening, proliferation of extrasubendothelialcellular matrix starts from basement membrane or basal layer, and then fascicular fibers are formed and mechanically fixed to basement.
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