Diagnosis of double-stranded RNA deficiency states - using mismatched double-stranded RAN, opt. administered with an interferon e.g. to treat hepatitis

摘要

The use of dsRNA for the mfr. of a medicament to treat a dsRNA-deficient disease state, excluding HIV infection or cancer, is claimed. Also claimed is a method for diagnosing a dsRNA deficient disease state comprising assaying a sample from a patient for dsRNA and comparing results with a normal control. More specifically, the dsRNA is mismatched and has formula r1n.r(C11-14(n. The dsRNA deficiency disease state is due to an immune disorder or viral infection, esp. chronic fatigue syndrome (CFS) and hepatitis infection.