2-substituted -1,4-dihydropyridines and pharmaceutical compositions containing them

摘要

Compounds of formula I <IMAGE> (I) wherein R is hydrogen or lower alkyl; R1 is acetyl, benzoyl, cyano, nitro, carboxy, alkoxycarbonyl or aminocarbonyl groups; R2 is an optionally substituted aryl or hetaryl residue; R3 is a carboxy or alkoxycarbonyl group; A is a cyclopropyl group or a group of formula -CH=CH- and R4 is a phenyl or heteroaryl group, optionally mono, di or tri-substituted, are useful in radical scavenging therapy.