发明名称 |
Novel naphthalene derivative |
摘要 |
Naphthalene derivative of the formula: <IMAGE> (I) wherein Ring A is a substituted or unsubstituted benzene ring; each of R1 and R2 is a group of the formula: -OR5, -NHR5 or <IMAGE> or either one of R1 and R2 is a lower alkoxy group and the other one is a group of the formula: -OR5, -NHR5 or <IMAGE> each of R3 and R4 is a lower alkoxy group, or one of R3 and R4 is a lower alkoxy group and the other is a hydrogen atom; R5 is a substituted alkyl group, a heterocyclic group, a cycloalkyl group, an alkyl group of at least 5 carbon atoms or alkenyl group; and each of R6 and R7 is hydrogen atom or a lower alkyl group and salts thereof are disclosed. Said naphthalene derivative (I) and its salts have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.
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申请公布号 |
US4840951(A) |
申请公布日期 |
1989.06.20 |
申请号 |
US19870064293 |
申请日期 |
1987.06.17 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
IWASAKI, TAMEO;TAKASHIMA, KOHKI |
分类号 |
A61K31/36;A61K31/165;A61K31/235;A61K31/357;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/535;A61K31/5375;A61P3/04;C07C67/00;C07C69/76;C07C69/767;C07C213/00;C07C231/00;C07C313/00;C07D213/30;C07D213/64;C07D213/65;C07D295/08;C07D295/088;C07D317/70 |
主分类号 |
A61K31/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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