| 摘要 |
PURPOSE:To obtain a large quantity of the title compound without using an expensive precursor, by culturing a microbial strain belonging to genus Citrobacter, requiring L-tyrosine for growth and capable of producing L- phenylalanine. CONSTITUTION:A microbial strain belonging to genus Citrobacter, requiring L-tyrosine for growth and capable or producing L-phenylalanine [e.g., Citrobacter freundii TYRA-1 (FERM P-9618)] is aerobically cultured in a liquid medium and L-phenylalanine produced and accumulated in the culture liquid is separated therefrom. The cultivation is carried out preferably at a medium pH of 5-9 and a culture temperature of 24-37 deg.C for 48-120hr. |
