发明名称 |
NOVEL DERIVATIVES OF GUANINE |
摘要 |
Antivirally active compounds of the formula <IMAGE> I wherein A is <IMAGE> (Aa) or <IMAGE> (Ab) wherein m is 1 or 2, n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1, Ra' is (CH2)pOH, NHCONH2 or CORa'', Ra'' is hydrogen, hydroxy or amino, p is 1 to 4, Rb' and Rb'' are independently selected from hydrogen or (CH2)pOH, with the proviso that at least one of Rb' or Rb'' is hydrogen; or Rb' and Rb'' together constitute an additional carbon-carbon bond to form an alkyne; or a physiologically acceptable salt, geometric or optical isomer thereof; pharmaceutical preparations containing the compounds and methods for treatment of virus infections. |
申请公布号 |
DE3477568(D1) |
申请公布日期 |
1989.05.11 |
申请号 |
DE19843477568 |
申请日期 |
1984.12.13 |
申请人 |
ASTRA LAKEMEDEL AKTIEBOLAG |
发明人 |
JOHANSSON, KARL, NILS-GUNNAR;LINDBORG, BJORN, GUNNAR;NOREN, JAN-OLOF |
分类号 |
C07D473/00;A61K31/52;A61K31/522;A61P31/12;A61P31/22;A61P35/00;A61P35/02;C07C43/174;C07C43/178;C07C43/315;C07D;C07D473/18;(IPC1-7):C07D473/18 |
主分类号 |
C07D473/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|