发明名称 |
N-substituted aliphatic heterocyclic compounds able to facilitate the passage of active substances through physiological barriers. |
摘要 |
<p>N-substituted aliphatic heterocyclic compounds having the following general formula: <CHEM> where Y is CH2, S, S>0 or 0; m and n are whole numbers between 0 and 10 and such that their sum is a whole number between 3 and 10; R is a C6-C20 linear or branched alkyl or an acyl of general formula - @-R1 in which R1 is a C5-C19 linear or branched alkyl; and a process for their production. Said compounds have low toxicity, and high capacity in facilitating the passage of active substances through physiological barriers. Said compounds also possess anti-inflammatory and antiallergic activity.</p> |
申请公布号 |
EP0314008(A2) |
申请公布日期 |
1989.05.03 |
申请号 |
EP19880117557 |
申请日期 |
1988.10.21 |
申请人 |
MEDIOLANUM FARMACEUTICI S.R.L. |
发明人 |
MERONI, CARLO;MAIORANA, STEFANO;RUGARLI, PIER LUIGI;PAGELLA, PIER GIUSEPPE |
分类号 |
A61K31/395;A61K31/535;A61K31/5375;A61K31/54;A61K31/55;A61P17/00;A61P29/00;A61P37/08;C07D295/00;C07D295/02;C07D295/03;C07D295/18;C07D295/185 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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