2-(IH-THIENO [3,2-C] PYRAZOL-3YL)-IH-INDOLE DERIVATIVES AND RELATED COMPOUNDS AS TEC KINASE INHIBITORS FOR THE TREATMENT OF INFLAMMATIONS AND IMMUNOLOGICAL DISORDERS
摘要
Disclosed are compounds of formula (I): (F) wherein Ri, R2, X and Ar are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
申请公布号
WO2007076228(A3)
申请公布日期
2007.08.30
申请号
WO2006US61649
申请日期
2006.12.06
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;BOEHRINGER INGELHEIM PHARMA GMBH & CO KG;BENTZIEN, JOERG, MARTIN;COOK, BRIAN, NICHOLAS;TAKAHASHI, HIDENORI