New heterocyclic derivatives.

摘要

New pharmacologically active heterocyclic derivatives as muscarinic receptor blocking agents, useful for the treatment of gastrointestinal disorders of the following formula <CHEM> wherein R is hydrogen atom or C1-9 alkyl optionally substituted by 2 or 3 radicals, which may be identical or different from each other, selected from aryl, cycloalkyl, hydroxy and carboxamide; R1 may be any group indicated for R, or NHR4, in which R4 is hydrogen atom, C1-4 alkyl substituted by -OOCR5, in which R5 is methyl substituted by 2 or 3 radicals, which may be identical or different from each other, selected from aryl, cycloalkyl and hydroxy, or a cycloalkyl substituted by another cycloalkyl; R2 is hydrogen atom, C1-4 alkyl, a radical -OOCR5, in which R5 is as hereinbefore defined; R3 is hydrogen atom or C1-4 alkyl; n is 0, 1 or 2 provided that at least one among R, R1, R2 and R3 is different from hydrogen atom. The tautomers of the compounds of formula (I) and acid addition salts thereof, as well as the processes for their preparation and pharmaceutical compositions containing them are also described