| 摘要 |
PURPOSE: To obtain the subject composition effective for preventing and treating parasitic infection of endoparasite and ectoparasite, comprising paraherquamide or dihydroparaherquamide as an active ingredient. CONSTITUTION: This composition comprises paraherquamide of formula I or dihydroparaherquamide of formula II or their mixture as an active ingredient. The compounds show activity as antiparasitic agent for parasite of endoparasite and ectoparasite, against parasite, especially vermes, ectoparasite and parasite infecting animal and plant such as insect, acarid mite and human body. The content of the active ingredient is 0.001-0.5wt.% in the case of liquid medicine, 0.005-5% in the case of parenteral administration medicine, 0.00001-0.002wt.% in the case of feed preparation, 0.005-2wt.% in the case of food premix and 0.0002-0.5wt.% in the case of supplement. The compound is obtained by culturing Penicillium charlesii MF5,120 (ATCC 20,841) as a new fungus and its variant. |
