发明名称 |
Intermediates for preparing 1,6-dicarba-vasopressin compounds |
摘要 |
New compounds which have potent V2-vasopressin antagonistic activity are prepared by a 1,6-cyclization using peptide bond formation. The structures of the compounds are characterized by the Pas1,6 or Tas1,6 cyclized unit. Also a chiral synthesis of the optically pure Pas intermediates is described.
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申请公布号 |
US4810778(A) |
申请公布日期 |
1989.03.07 |
申请号 |
US19880191673 |
申请日期 |
1988.05.09 |
申请人 |
SMITHKLINE BECKMAN CORPORATION |
发明人 |
CALLAHAN, JAMES F.;HUFFMAN, WILLIAM F.;NEWLANDER, KENNETH A.;YIM, NELSON C. F. |
分类号 |
A61K38/00;C07K7/16;(IPC1-7):C07K7/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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