发明名称 RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES
摘要 The present invention provides novel renin-inhibiting peptides of the formula X-A6-B7-C8-D9-E10-F11-G12-H13-I14-Z, containing aryl acid derived moieties of the formula XL2b which are substituted for Phe<8>-His<9>, X and Z are terminal groups, and the remaining variables are absent or are amino acid residues. Such inhibitors are useful for the diagnosis and control of renin-dependent hypertension and other related diseases.
申请公布号 WO8901488(A1) 申请公布日期 1989.02.23
申请号 WO1988US02255 申请日期 1988.07.11
申请人 THE UPJOHN COMPANY 发明人 TEN BRINK, RUTH, E.
分类号 C12N9/99;A61K31/16;A61K38/43;A61K38/55;A61P9/12;C07C65/21;C07C65/24;C07C69/92;C07C235/16;C07C323/12;C07D209/08;C07D213/81;C07D215/14;C07D263/06;C07F7/18;C07K5/02;C07K5/06;C07K7/02;C07K14/81;(IPC1-7):C07K5/02;A61K37/64 主分类号 C12N9/99
代理机构 代理人
主权项
地址