| 发明名称 |
MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES |
| 摘要 |
The present invention provides novel renin-inhibiting peptides of the formula Z-C(O)-CH(OH)-CH(CH2R1)-C(O)-N(R2)-CH(CH2R3)-C(O)-NH-CH(CH2R4)-X-C(R5) (R2)-C(O)-Y-Z containing malic acid derivatives. Such inhibitors are useful for the diagnosis and control of renin-dependent hypertension and other related diseases. |
| 申请公布号 |
WO8900161(A1) |
申请公布日期 |
1989.01.12 |
| 申请号 |
WO1988US01535 |
申请日期 |
1988.05.13 |
| 申请人 |
THE UPJOHN COMPANY |
发明人 |
THAISRIVONGS, SUVIT |
| 分类号 |
C12N9/99;A61K31/495;A61K31/496;A61K31/535;A61K31/5355;A61K31/5375;A61K31/66;A61K38/55;A61P5/38;A61P9/00;A61P9/12;A61P43/00;C07D217/24;C07D233/54;C07D235/18;C07D295/18;C07D401/12;C07K5/06;C07K14/81;(IPC1-7):C07D401/12 |
主分类号 |
C12N9/99 |
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