Peptide derivatives and their therapeutic application.

摘要

Peptide derivatives of formula X - Lys - Gln - Y - Gly - Asp - Z - W (I> in which X denotes hydrogen, an amino acid residue, a group of formula DE where D denotes a physiologically acceptable N-protective group or hydrogen and where E denotes a single bond or an amino acid residue, Y denotes an L-arginyl or D-arginyl residue, Z denotes an L-valyl, D-valyl, L-phenylalanyl, D-phenylalanyl, L-seryl or D-seryl residue, W denotes an OH, NH2 or O-R<1> group with R<1> denoting a C1-C4 alkyl radical NHR<2>, with R<2> denoting a C1-C4 alkyl radical or an amino acid residue.