发明名称 BISPHENYLALKYLPIPERAZINDERIVATER OG FREMGANGSMAADE TIL FREMSTILLING DERAF
摘要 The present invention relates to previously unknown compounds of the formula I <IMAGE> where R1 and R2 are identical or different and selected from hydrogen and halogen; R3 and R4 are identical or different and selected from hydrogen or lower alkyl; n is the number 2 or 3; A is selected from the pyrimidyl or pyridyl groups (a), (b), (c) and (d), <IMAGE> where R5 is selected from hydrogen, lower alkyl and halogen, R6 and R7 are identical or different and selected from hydrogen, halogen, lower alkyl, electron donor groups such as lower alkoxy or hydroxyl, or electron acceptor groups such as cyano, nitro, trifluoromethyl, COOR8, CONR9R10 or CO-B; where R8 denotes hydrogen or lower alkyl; R9 and R10 are identical or different and selected from hydrogen, lower alkyl and cycloalkyl; B is selected from (e) and (f), <IMAGE> where m denotes the number 1, 2, 3 or 4, R1 is selected from hydrogen or lower alkyl, and the pharmacologically active salts thereof. The novel compounds can be used for treating mental illnesses.
申请公布号 DK671588(A) 申请公布日期 1988.12.01
申请号 DK19880006715 申请日期 1988.12.01
申请人 LEO, AKTIEBOLAGET 发明人 FEX, TOMAS;OLSSON, KNUT GUNNAR;ABRAMO, AINA LISBETH;CHRISTENSSON, ERIK GUNNAR;LUNDSTEDT, TORBJOERN ERIK
分类号 A61K31/495;A61K31/505;A61K31/535;A61K31/55;A61P25/00;A61P25/18;A61P25/20;A61P25/24;A61P25/26;C07D;C07D213/00;C07D213/72;C07D213/74;C07D213/76;C07D213/80;C07D213/81;C07D213/82;C07D213/85;C07D239/42;C07D401/00;C07D401/04;C07D401/06;C07D403/00;C07D403/04;(IPC1-7):C07D213/74;C07D213/79 主分类号 A61K31/495
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