2-Selenomethyl-1, 4-dihydropyridines, a process for the preparation thereof and pharmaceutical compositions containing them.

摘要

Compounds of formula I <CHEM> wherein: R1 is a cyano, nitro, acetyl, benzoyl or alkoxycarbonyl group; R2 is an optionally substituted phenyl or hetaryl group; R3 is an alkoxycarbonyl group; R4 is an alkyl group, optionally substituted by hydroxy, amino, phenyl, heterocyclic group; an optionally substituted phenyl group or an heterocyclic group. Compounds I are useful in human therapy as agents able to interact with Ca<+><+>-dependent systems and as anti-tumor agents.