发明名称 FATTY ACID ESTER, REAGENT CONTAINING SAID ESTER FOR MEASURING LIPASE ACTIVITY AND METHOD FOR MEASURING LIPASE ACTIVITY USING SAID REAGENT
摘要 NEW MATERIAL:A fatty acid ester expressed by formula I (R1 is 7-17C straight-chain alkyl; R2 is H, halogen, alkyl or hydroxyl group; R3 is H, sulfoxyl, carboxyl, hydroxyl group or alkyl; X is H, sulfoxyl or carboxyl). EXAMPLE:4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bisphenol S,S-dioxide lauric acid ester. USE:Useful as a substrate for measuring lipase activity, having water solubility and optical absorption band at long wavelengths and capable of measuring enzymic activity, such as lipase without suffering from interference by visible absorption of pigments in blood and further rapid analysis and measurement with high quantitative sensitivity. PREPARATION:For example, phenolphthalein coloring matter is reacted with an anhydride of a higher fatty acid in the presence of an acid capturing agent in a solvent to afford the aimed compound expressed by formula I.
申请公布号 JPS63275579(A) 申请公布日期 1988.11.14
申请号 JP19870109539 申请日期 1987.05.01
申请人 EIKEN KAGAKU KK 发明人 SATO KAZUHIKO
分类号 G01N33/50;C07D327/04;C12Q1/44 主分类号 G01N33/50
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