| 摘要 |
PURPOSE:To obtain the titled compound useful as a synthetic intermediate for pharmaceuticals, agricultural chemicals, liquid crystal compound, etc., in high quality without causing the problems of by-product and post-treatment, by oxidizing cuminaldehyde under alkaline condition using hydrogen peroxide as an oxidizing agent. CONSTITUTION:The objective compound of formula II can be produced by oxidizing cuminaldehyde of formula I using hydrogen peroxide as an oxidizing agent under alkaline condition (preferably using sodium hydroxide, potassium hydroxide, etc., to maintain the alkaline state). The above reaction is carried out in a hydrophilic organic solvent such as methanol or dioxane which may contain water. The hydrogen peroxide as an oxidizing agent is usually used as an aqueous solution having a concentration of about 10-40% and the amount of the peroxide is preferably about 1.5-2.5 times mol of the stoichiometric amount based on the cuminaldehyde. The reaction temperature is usually about 60-100 deg.C.
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