摘要 |
<p>Bicyclic phenol ethers of the formula (I): (I) wherein R1 is a hydrogen atom or a lower alkyl radical, R2 is a hydrogen atom or an acyl radical, X is an oxygen or sulphur atom or an -NH- group, Y is a -CO-CHR3- group or a -CO-C=CR4R5 group, R3 is a hydrogen atom, a lower alkyl radical, which can optionally be substituted by an aryl radical, or a cycloalkyl radical containing 3 to 7 carbon atoms and R4 and R5, which can be the same or different, are hydrogen atoms, lower alkyl radicals, alkenyl radicals containing 2 to 16 carbon atoms, which can optionally be substituted by an aryl radical, or an aryl radical or R4 and R5, together with the carbon atom to which they are attached, form a cycloalkyl ring containing 3 to 7 carbon atoms, and pharmaceutically acceptable, pharmacologically compatible salts thereof have an inhibiting action on anaphylactic reactions of the skin and of the bronchial system, even when administered orally in low dosages.</p> |