| 摘要 |
PURPOSE:To obtain the titled composition, capable of being selectively incorporated into tumorous cells and exhibiting cellulicidal effects of a photosensitive substance by subsequent irradiation with light, by blending an oily contrast medium with the photosensitive substance soluble therein. CONSTITUTION:A composition obtained by blending an oily contrast medium, preferably iodinated poppy seed oil fatty acid ester (particularly lipiodol which is ethyl ester) with a photosensive substance soluble therein, preferably a photosensitive substance excited by rays having high tissue penetrability (particularly rays at >=650nm wavelength), e.g. pheophorobide a or phthalocyanine derivative. The above-mentioned composition is administered and rays, preferably laser beams are irradiated after 6-24hr to excite the photosensitive substance and activate oxygen molecules. Thereby active oxygen is induced to exhibit cellulicidal effects on tumorous cells.
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