| 摘要 |
PURPOSE:To efficiently obtain fluoroalkylated acetylenes useful as industrial raw materials, etc., by reacting a specific perhaloalkane with an acetylene derivative in the presence of an enzyme. CONSTITUTION:One equiv. perhaloalkane expressed by formula I (X and Y are same or different halogen; Z is Br or I; n is 0 or >=1) (e.g. perfluoroalkyl iodide) and 1-100 equiv. acetylene derivative expressed by formula II [R1 and R2 are same or different H, (ar)alkyl or aryl] are added to a solvent containing water. An enzyme having metallic ions as a prosthetic group (e.g. urease having Ni) is then added to the solvent and, as necessary, a surfactant is added and reacted at 0-55 deg.C to form perfluoroalkylethylenes expressed by formula III.
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