| 发明名称 |
High yield production of active Factor IX |
| 摘要 |
PCT No. PCT/US86/00817 Sec. 371 Date May 5, 1986 Sec. 102(e) Date May 5, 1986 PCT Filed Apr. 17, 1986 PCT Pub. No. WO86/06408 PCT Pub. Date Nov. 6, 1986.High yields of active Factor IX are produced by culturing a CHO cell line transfected with chromosomally-integrated Factor IX cDNA in medium to which vitamin K is added.
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| 申请公布号 |
US4770999(A) |
申请公布日期 |
1988.09.13 |
| 申请号 |
US19860929294 |
申请日期 |
1986.05.05 |
| 申请人 |
GENETICS INSTITUTE, INC. |
发明人 |
KAUFMAN, RANDAL J.;SHOEMAKER, CHARLES B.;WASLEY, LOUISE C. |
| 分类号 |
C12N15/00;C12N5/10;C12N9/64;C12N15/09;C12P21/02;C12R1/91;(IPC1-7):C12P21/00;C12P19/34;C12N1/20 |
主分类号 |
C12N15/00 |
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代理人 |
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| 主权项 |
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