发明名称 |
ASPERGILLUS NIDULANS ISOPENICILLIN-N-SYNTETAS KODANDE REKOMBINANT-DNA-EXPRESSIONSVEKTORER OCH DNA-SEKVENSER. |
摘要 |
DNA compounds and recombinant DNA expression vectors that encode and drive expression in recombinant host cells of the isopenicillin N synthetase activity of Aspergillus nidulans are useful to produce isopenicillin N synthetase and to improve the yield of beta -lactam-containing antibiotics from antibiotic-producing organisms. The isopenicillin N synthetase gene of A. nidulans can be isolated from plasmid pOGO4. |
申请公布号 |
FI884112(A0) |
申请公布日期 |
1988.09.07 |
申请号 |
FI19880004112 |
申请日期 |
1988.09.07 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
INGOLIA, THOMAS DOMINICK;QUEENER, STEPHEN WYATT;SKATRUD, PAUL LUTHER;WEIGEL, BARBARA JEAN |
分类号 |
C07H21/04;C12N1/14;C12N1/20;C12N1/21;C12N9/00;C12N15/00;C12N15/09;C12N15/54;C12N15/70;C12R1/19;C12R1/66;C12R1/745;C12R1/80 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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