Test kit, extraction device and method for the determination of streptococcus a antigen.

摘要

A test kit useful for the determination of Streptococcus A antigen comprises: (i) an immunoreactive reagent comprising either Streptococcus A antigen or antibodies attached to water-insoluble particles, (ii) a substrate having thereon a dried, binder-free coating of a first extraction reagent, (iii) an aqueous solution of a second extraction reagent, and (iv) a neutralizing solution. Both extraction reagents combine to provide nitrous acid. In addition, an extraction device includes a water-insoluble container having affixed therein an extraction reagent and an applicator means for collecting and depositing a biological specimen within the container. The extraction device and test kit are useful for the determination of Streptococcus A antigen in a biological specimen.