发明名称 SUPPRESSIVE AGENT FOR GASTROINTESTINAL PERISTALSIS
摘要 PURPOSE:To obtain the titled suppressive agent comprising an aqueous solution containing scopolia extract and a salt having buffering action. CONSTITUTION:A suppressive agent for gastrointestinal peristalsis comprising an aqueous solution containing 0.01-1w/v% scopolia extract and 0.01-1w/v% inorganic or organic salt having buffering action (e.g. sodium metaphosphate, acidic sodium pyrophosphate, sodium phosphate, sodium citrate, etc.) as active ingredients. A dose of scopolia extract when the suppressive agent is used is 2-200mg/time, preferably 10-50mg/time. A saccharide such as white sugar, lactose, fructose, glucose, etc., sugaralcohol such as D-sorbitol, etc., are used as a water-soluble excipient. The suppressive agent has low side effects such as hydrodipsia, motor ataxia, etc., and made into a form to be readily administered and medicated with a relatively small amount of water. The suppressive agent has relatively immediate effects and continues the effects for 30-90min.
申请公布号 JPS63198634(A) 申请公布日期 1988.08.17
申请号 JP19870029572 申请日期 1987.02.13
申请人 TAKADA SEIYAKU KK 发明人 HIRANO TSUTOMU;IRINO TORU;OGAWARA YOJI;DOI NORITOSHI;YONETANI AKIMASA
分类号 A61K36/81;A61K31/19;A61K33/42;A61K36/00;A61P1/00 主分类号 A61K36/81
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