摘要 |
1,137,142. Microbiological preparation of androsta - 1,4 - diene - 3,17 - dione. RICHTER GEDEON VEGYESZETI GYAR R.T. 1 March, 1966 [5 March, 1965], No. 8964/66. Heading C2U. The invention comprises a process for preparing androsta - 1,4 - diene - 3,17 - dione by treating cholest-4-en-3-one under aerobic conditions, in the presence of an 8-hydroxy-quinoline, with cells of Mycobacterium smegmatis developed on a semi-synthetic fermentation medium. The product may be isolated as the #-naphthol molecular complex. |