发明名称 ERGOLINYL HETEROCYCLES
摘要 Ergoline derivatives of the formula I <CHEM> wherein R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a methoxy group; R3 represents a hydrocarbon group having from 1 to 4 carbon atoms; X represents a nitrogen atom and Y represents an oxygen atom, a - @-R4 or a -N=@-R5 group wherein R4 represents a hydrogen atom, a C1-C4 alkyl or a phenyl group, R5 represents a hydrogen atom, a C1-C4 alkyl, a phenyl, an amino or di(C1-C4 alkyl)amino group and the nitrogen atom of the group -N= @-R5 is not joined to the nitrogen atom represented by X, or Y represents a nitrogen atom and X represents an oxygen atom or a - @-R4 group wherein R4 is as above defined; and the pharmaceutically acceptable salt thereof; are useful for treatment of Parkinsonism and dyskinetic syndromes.
申请公布号 ZA8800687(B) 申请公布日期 1988.08.02
申请号 ZA19880000687 申请日期 1988.02.01
申请人 FARMITALIA CARLO ERBA S.P.A. 发明人 ENZO BRAMBILLA;SERGIO MANTEGANI;LORENZO PEGRASSI;ALESSANDRO ROSSI;ALDEMIO TEMPERILLI
分类号 A61K31/48;A61P25/00;C07D457/00;C07D457/02 主分类号 A61K31/48
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