发明名称 NITROXIDE COMPOUNDS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION INTENDED FOR THE PROPHYLAXIS AND TREATMENT OF ISCHEMIC CELL DAMAGE
摘要 The use of an organochemical compound comprising the structural unit where R is selected from the group consisting of (i) unpaired electron, (ii) a cation such as a physiologically acceptable metal ion, (iii) hydrogen and (iv) a protective group which is known per se for hydroxyl groups and which can readily be cleaved off, and the alpha and alpha' carbon atoms are substituted in a manner such that if R = unpaired electron the compound is a stable nitroxide (stable nitroxyl radical), for the preparation of a pharmaceutical composition intended for the prophylaxis and treatment of ischemic cell damage. The use comprises a method of preventing and treating ischemic cell damage in nammals.
申请公布号 AU1107888(A) 申请公布日期 1988.07.27
申请号 AU19880011078 申请日期 1987.12.22
申请人 PHARMACIA A.B. 发明人 ANN-CHRISTIN MARTA BYLUND-FELLENIUS;ULF ANDERS NILSSON
分类号 C07D263/04;C07D295/24 主分类号 C07D263/04
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